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The integration of these factors into a multidisciplinary approach, based on updated guidelines and adapted to the individual patient’s characteristics, represents a fundamental prerequisite for optimizing the benefits of GLP-1 therapy [96]
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injections of 100 nmol kg −1 MK-801 ( n = 8 mice), 100 nmol kg −1 GLP-1 ( n = 8 mice), 100 nmol kg −1 GLP-1–MK-801 ( n = 8 mice) or vehicle (isotonic saline, n = 8 mice) at a volume of 5 µl g −1
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